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Alcohol Use Curbed By Anti-nausea Medication

Gx) in a controlled, double-blind clinical trial. Subjects received either ondansetron or placebo for 11 weeks, and all received standard cognitive behavioral therapy. For subjects with the LL/TT genotype, those treated with ondansetron, on average, fell below the high-risk drinking category, while those who received placebo remained in the high-risk category. In addition, these same genotype categories responded more positively to ondansetron, versus placebo, in increasing the days of abstinence. The finding appeared online and will be published in the March issue of the American Journal of Psychiatry. More News on I agree to the terms and conditions Your comments are automatically posted once they are submitted. All comments are however constantly reviewed for spam and irrelevant material (such as product or personal advertisements, email addresses, telephone numbers and website address).
For the original version including any supplementary images or video, visit http://www.medindia.net/news/Anti-nausea-Medication-for-Alcoholism-Treatment-79751-1.htm

The medication, ondansetron (Zofran), could become a readily available therapy for helping some alcoholics become abstinent. The study, published Wednesday in the American Journal of Psychiatry , is based on research on a gene known as 5-HTT that is important to the serotonin system of the brain. Certain variants of this gene can increase the risk of psychiatric disorders, such as depression, anxiety, obsessive-compulsive disorder and addiction. Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy. But it's in a class of medications that work by blocking serotonin. The study tested the idea that a drug to block this neurotransmitter in genetically susceptible people might reduce the severity of their drinking. Researchers analyzed the genotype of 283 alcoholics who were still drinking.
For the original version including any supplementary images or video, visit http://articles.latimes.com/2011/jan/21/news/la-heb-alcoholism-20110121

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